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Showing posts with label Alzheimer's / Dementia News. Show all posts
Showing posts with label Alzheimer's / Dementia News. Show all posts

Misconceptions About Alzheimer's Varies Among Races

Alzheimer's disease is still a mystery to people of different races and a large percentage of people across the board are unaware that treatments are available to reduce symptoms.

This is one of the surprising findings in a national survey, "Public opinion about Alzheimer's disease among Blacks, Hispanics, and Whites," which was analyzed by researchers at the University of Michigan School of Public Health. Understanding racial and ethnic influences on knowledge and beliefs about Alzheimer's is critical to communicating risk reduction strategies, symptom recognition, diagnosis and illness management, the paper said.

There were more similarities in patterns of response among the racial groups than expected, said Cathleen Connell, professor in the U-M School of Public Health and director of the Education and Information Transfer Core of the Michigan Alzheimer's Disease Research Center. One half of the sample reported that nothing can be done to maintain cognitive functioning and reduce Alzheimer's risk. Similarly, less than half of the sample was aware that treatments can address symptoms and improve quality of life. There were no significant differences among races in the level of concern about getting Alzheimer's disease.


Click here to see the rest of this article in Medical News Today
Reprinted with kind permission from http://www.medicalnewstoday.com/


Gene Therapy Reduces Amyloid Plaques In Mice With Model Of Alzheimer Disease

A new gene therapy technique has been shown to reduce the amount of amyloid-beta protein (which forms the plaques found in the brains of people with Alzheimer's disease) in the brains of mice. In a paper published this week in the open access medical journal PLoS Medicine Matthew Hemming, Dennis Selkoe and colleagues from Harvard Medical School generated a secreted form of neprilysin, a protease that can break down amyloid-beta protein, and used primary fibroblasts to introduce this soluble protease into the brains of mice who had advanced plaque deposition.

The pathologic hallmarks of Alzheimer disease are extracellular plaques of amyloid-beta protein and intraneuronal neurofibrillary tangles of tau protein, both of which accumulate in the regions of the brain that mediate memory and thought. Current treatments for Alzheimer disease affect only the symptoms. Ultimately it is to be hoped that it would be possible to develop disease-modifying interventions that would lower the production of amyloid-beta protein or enhance its clearance.


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